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April 2025, Vol 31, No. 2

Pharmaceutical Sciences is a peer-reviewed, and quarterly journal providing a forum for basic to clinical issues related to all areas of pharmaceutical sciences. It is the official journal of Faculty of Pharmacy, published by TUOMS PRESS, Tabriz University of Medical Sciences.
- Platinum Open Access (no processing or publication fees)
- Indexed in Web of Science Core Collection (Impact Factor 2023= 1.4) and Scopus (CiteScore 2023= 2.6-Q2)
- Average time to first decision in 2024 (all decisions): 15 days
- Time to first post-review decision in 2024: 2-10 weeks
- Acceptance rate in 2024: 10%
- Publications from 21 countries in 2024

Original Research

1. Comparison Effects of Methanolic Extracts of Salvia Macrosiphon and Withania Coagulans on Withdrawal Syndrome in Mice

Mohammad Karami, Ahmad Reza Gohari, Farshad Naghshvar, Almira salarnia, sharbano Alemy

Pharm Sci. 2012;18(3): 183-186.

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Original Research

2. Evaluation of cytotoxic effect of methanolic extract fractions of Ornithogalum cuspidatum on WEHI-164 fibrosarcoma cancer cell line

S Valiyari*, H Asadi, B Baradaran, Z Babaloo, A Delazar, M Bannazadeh Amirkhiz

Pharm Sci. 2012;18(1): 19-24.

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Original Research

3. Simvastatin Treatment is not Associated with Changes in Serum Concentrations of Heat Shock Proteins -60 and -70 in Patients with Dyslipidemia

Roya Aryanpour, Seyed Mohammad Reza Parizadeh, Mohsen Moohebati, Shima Tavallaie, Amir Hossein Sahebkar, Shabnam Mohammadi, Majid Ghayour*, Gordon AA. Ferns

Pharm Sci. 2014;20(2): 46-51.

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Research Article

4. Inhibitory Effects of Urginea maritima (L.) Baker, Zhumeria majdae Rech. F. and Wendelbo and Physalis divaricata D. Don Ethanolic Extracts on Mushroom Tyrosinase

Foroogh Namjoyan, Alireza Jahangiri, Mohammad Ebrahim Azemi, Hamideh Mousavi*

Pharm Sci. 2016;22(2): 81-86. doi: 10.15171/PS.2016.14

Scopus ID: 84977138905

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Short Communication

5. Contact Toxicity and Chemical Composition of Essential Oil of Acantholimon scorpius

Ardalan Pasdaran Lashgari*, Abbas Delazar, Farriba Hesmati Afshar, Dena Parsa

Pharm Sci. 2016;22(2): 138-141. doi: 10.15171/PS.2016.22

Scopus ID: 84977118625

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Research Article

6. Comparison of Three Different Diet-Induced Non Alcoholic Fatty Liver Disease Protocols in Rats: A Pilot Study

Sara Shojaei Zarghani, Hamid Soraya, Leila Zarei, Mohammad Alizadeh*

Pharm Sci. 2016;22(1): 9-15. doi: 10.15171/PS.2016.03

Scopus ID: 84963522493

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Research Article

7. Antibacterial and Antioxidant Activities of the Volatile Composition of the Flower and Fruit of Solanum sisymbriifolium (Litchi Tomato)

Ardalan Pasdaran*, Arsalan Pasdaran, Nazim Mamedov

Pharm Sci. 2017;23(1): 66-71. doi: 10.15171/PS.2017.10

Scopus ID: 85018487068

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Research Article

8. Radiographic and Histopathologic Analysis on Osteoarthritis Rat Model Treated with Essential Oils of Rosmarinus officinalis and Populus alba

Hamza Belkhodja*, Boumediene Meddah, Aicha Meddah TirTouil, Khaled Slimani, Abdenacer Tou

Pharm Sci. 2017;23(1): 12-17. doi: 10.15171/PS.2017.03

Scopus ID: 85018491834

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Research Article

9. Cardioprotective Effects of Rosmarinic Acid on Isoproterenol-Induced Myocardial Infarction in Rats

Negisa Seyed Toutounchi, Arash Afrooziyan, Maryam Rameshrad, Aysa Rezabakhsh, Haleh Vaez, Sanaz Hamedeyazdan, Fatemeh Fathiazad, Alireza Garjani*

Pharm Sci. 2017;23(2): 103-111. doi: 10.15171/PS.2017.16

Scopus ID: 85023198960

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Research Article

10. Microextraction of Furosemide from Human Serum and Its Fluorimetric Determination

Akbar Rezazadeh, Mohammad Amjadi, Jamshid L Manzoori, Alireza Ghaffari, Abolghasem Jouyban*

Pharm Sci. 2018;24(1): 71-78. doi: 10.15171/PS.2018.11

Scopus ID: 85046097944

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Research Article

11. Probing Angiotensin Converting Enzyme (ACE) Domain-Dependent Inhibition of Onopordia, Isolated from Onopordon acanthium L., Using a Continuous Fluorescent Assay

Niusha Sharifi, Khosro Khajeh, Shabnam Mahernia, Saeed Balalaie, Ghasem Ataie, Raheleh Jahanbani, Massoud Amanlou*

Pharm Sci. 2018;24(1): 31-37. doi: 10.15171/PS.2018.06

Scopus ID: 85046094048

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Short Communication

12. Solubility and Apparent Specific Volume of Sucrose in Some Aqueous Polyethylene Glycol Mixtures at 298.2 K

Dario A Tinjaca, Maria M Muñoz, Elaheh Rahimpour, Abolghasem Jouyban, Fleming Martinez*, William E Acree Jr

Pharm Sci. 2018;24(2): 163-167. doi: 10.15171/PS.2018.24

Scopus ID: 85049301646

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Research Article

13. Formulation, Characteristic Evaluation, Stress Test and Effectiveness Study of Matrix Metalloproteinase-1 (MMP-1) Expression of Glutathione Loaded Alginate Microspheres and Gel

Dewi Melani Hariyadi*, Noorma Rosita , Fitria Nugrahaeni

Pharm Sci. 2018;24(4): 304-312. doi: 10.15171/PS.2018.44

Scopus ID: 85060024188

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Research Article

14. The Ameliorative Effects of Allopurinol on Paraquat-Induced Pulmonary Fibrosis in Rats

Saeedeh Shariati, Mohammad Javad Khodayar* , Aliasghar Hemmati, Mehdi Goudarzi, Milad Kiani, Anahita Rezaei

Pharm Sci. 2019;25(1): 11-16. doi: 10.15171/PS.2019.2

Scopus ID: 85065644606

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Research Article

15. Apparent Specific Volumes of Sucrose in Different Aqueous Cosolvent Mixtures at 298.2 K

Dario A Tinjaca, Maria M Muñoz, Fleming Martinez* , Abolghasem Jouyban, William E Acree Jr

Pharm Sci. 2018;24(4): 324-331. doi: 10.15171/PS.2018.46

Scopus ID: 85060029866

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Research Article

16. Combined Use of Polymers and Porous Materials to Enhance Cinnarizine Dissolution

Maryam Maghsoodi* , Fatemeh Shahi

Pharm Sci. 2019;25(4): 331-337. doi: 10.15171/PS.2019.44

Scopus ID: 85077549880

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Research Article

17. MCF-7 and its Multidrug Resistant Variant MCF-7/ADR Overcome TNF Cytotoxicity through Prevention of Reactive Oxygen Species Accumulation

Morteza Ghandadi , Javad Behravan, Samira Biabani, Sara Abbaspor, Fatemeh Mosaffa*

Pharm Sci. 2019;25(2): 118-123. doi: 10.15171/PS.2019.18

Scopus ID: 85069209477

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Short Communication

18. Phytochemicals and Tyrosinase Inhibitory Activity from Piper caninum and Piper magnibaccum

Nur Athirah Hashim, Farediah Ahmad, Wan Mohd Nuzul Hakimi Wan Salleh* , Shamsul Khamis

Pharm Sci. 2019;25(4): 358-363. doi: 10.15171/PS.2019.47

Scopus ID: 85077620428

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Research Article

19. Euphorbia prostata Exerts Potent Anti-Inflammatory and Anti-Arthritic Activity in Downregulating the Increased Expression of Pro-Inflammatory Cytokines

Dewi Melani Hariyadi* , Vikram Kumar Sahu

Pharm Sci. 2020;26(4): 370-378. doi: 10.34172/PS.2020.51

Scopus ID: 85101500324

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Research Article

20. A Fast and Robust Approach for the Green Synthesis of Spherical Magnetite (Fe₃O₄) Nanoparticles by Tilia tomentosa (Ihlamur) Leaves and its Antibacterial Studies

Shashanka Rajendrachari* , Abdullah Cahit Karaoglanli, Yusuf Ceylan, Orhan Uzun

Pharm Sci. 2020;26(2): 175-183. doi: 10.34172/PS.2020.5

Scopus ID: 85086035058

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Short Communication

21. Antityrosinase Inhibitory Activity of Phytochemicals from Alpinia aquatica Roscoe

Nissha Bharrathi Romes , Wan Mohd Nuzul Hakimi Wan Salleh* , Hasnah Mohd Sirat* , Zaini Assim

Pharm Sci. 2020;26(2): 209-213. doi: 10.34172/PS.2020.6

Scopus ID: 85089456433

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Review

22. The Effects of N-acetylcysteine on Inflammatory Markers and Homocysteine: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Jamal Hallajzadeh , Alireza Milajerdi, Željko Reiner, Fariba Kolahdooz, Zatollah Asemi*

Pharm Sci. 2020;26(3): 214-224. doi: 10.34172/PS.2020.30

Scopus ID: 85096525160

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Research Article

23. A Comparison on Effects of High Dose Rosuvastatin versus High Dose Atorvastatin on Lipid Profile and CRP Level in Patients Undergoing Percutaneous Coronary Intervention: A Randomized Study

Mahboubeh Darban , Elham Yusefabadi, Majid Mirmohammad Khani, Bahram Sohrabi, Bahador Bagheri*

Pharm Sci. 2021;27(4): 568-574. doi: 10.34172/PS.2021.5

Scopus ID: 85127106747

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Research Article

24. Fast-Dissolving Sublingual Nanofibers of Ondansetron Hydrochloride: Formulation, Physicochemical Characterization, and Clinical Evaluation on Post-cataract Surgery Patients

Samira Kamranpour , Shahla Mirzaeei* , Farid Daneshgar , Farid Najafi

Pharm Sci. 2022;28(1): 101-111. doi: 10.34172/PS.2021.24

Scopus ID: 85127191879

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Review

25. Nicolau Syndrome: A Review of Case Studies

Paria Mojarrad , Hamid Mollazadeh , Behnaz Barikbin , Mohammad Bagher Oghazian*

Pharm Sci. 2022;28(1): 27-38. doi: 10.34172/PS.2021.32

Scopus ID: 85121689958

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Research Article

26. Design and Evaluation of Novel Sustained-Release Floating Microspheres for Oral Delivery of Ciprofloxacin Hydrochloride

Parisa Soraya Asa , Shahla Mirzaeei*

Pharm Sci. 2022;28(2): 331-339. doi: 10.34172/PS.2021.45

Scopus ID: 85132860922

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Research Article

27. Synthesis of Novel Androstane-N-Cyclohexyl-17-Carboxamides, and Their Effect on the 5α-Reductase Isoform 2, the Androgen Receptor, and Androgen-Dependent Glands

Juan C. Lopez-Lezama , Marisa Cabeza , Yvonne Heuze , Araceli Sánchez, José L. Rojas , Norma A. Valencia-Islas*

Pharm Sci. 2022;28(3): 433-442. doi: 10.34172/PS.2021.74

Scopus ID: 85139838506

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Mini Review

28. **A Mini Review of Neuropharmacological Effects of Rosa damascena Herrm**

Farimah Beheshti , Somaieh Ahmadabady, Yousef Baghcheghi, Akbar Anaeigoudari* , Mahmoud Hosseini

Pharm Sci. 2022;28(2): 232-238. doi: 10.34172/PS.2021.49

Scopus ID: 85132897520

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Research Article

29. Development of a Nanocluster-Based Platform for Determination of Sofosbuvir

Zahra Karimzadeh , Abolghasem Jouyban , Elaheh Rahimpour*

Pharm Sci. 2022;28(3): 443-448. doi: 10.34172/PS.2021.57

Scopus ID: 85133265760

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Research Article

30. **MicroRNA 138 Upregulation is Associated with Decreasing Levels of CCND1 Gene Expression and Promoting Cell Death in Human Prostate Cancer Cell Lines**

Nasrin Haghighi-Najafabadi , Shima Fayaz, Mahboubeh Berizi, Ghazal Haddad , Pezhman Fard-Esfahani*

Pharm Sci. 2023;29(4): 486-494. doi: 10.34172/PS.2023.17

Scopus ID: 85174403512

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Review Article

31. Targeting Pharmacological and Nanotechnology Based Therapeutics for Management of Hirsutism: A Comprehensive State-of-the-Art

Ishrat Zahoor , Sukhbir Singh* , Neelam Sharma , Ikmeet Kaur Grewal, Shahid Nazir Wani

Pharm Sci. 2024;30(1): 54-69. doi: 10.34172/PS.2023.24

Scopus ID: 85181571134

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Research Article

32. Response Surface Methodology Approach to Optimize the Expression of Thioredoxin-MOG Fusion Protein

Maryam Radmard , Atieh Hashemi*

Pharm Sci. 2024;30(2): 252-261. doi: 10.34172/PS.2024.1

Scopus ID: 85189306629

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Research Article

33. Biogenic Zinc Oxide Nanoparticles Attenuate Acute Lymphoblastic Leukemia Cell Proliferation through Oxidative Stress and DNA Damage

Venugopal Sujatha* , Alagesan Venkatesan, Acharya Sancharan, Chinnasamy Thirunavukkarasu

Pharm Sci. 2024;30(2): 262-273. doi: 10.34172/PS.2024.4

Scopus ID: 85189473247

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Research Article

34. Can L-Carnitine Replace Tumor Necrosis Factor-Alpha Blockers? A Systematic Review and Dose–Response Meta-Analysis

Farnaz Naeimzadeh , Amirreza Naseri , Sarvin Sanaie , Seiedhadi Saghaleini , Afshin Gharekhani*

Pharm Sci. 2024;30(4): 432-443. doi: 10.34172/PS.2024.13

Scopus ID: 85205787894

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Review Article

35. Vesicular Carriers for Follicular Drug Delivery

Mostafa Amirinejad , Atoosa Haghighizadeh, Leila Etemad, Omid Rajabi*

Pharm Sci. 2025;31(1): 22-42. doi: 10.34172/PS.024.40827

Scopus ID: 85215239549

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Indexing & Abstracting:

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1. Comparison Effects of Methanolic Extracts of Salvia Macrosiphon and Withania Coagulans on Withdrawal Syndrome in Mice

2. Evaluation of cytotoxic effect of methanolic extract fractions of Ornithogalum cuspidatum on WEHI-164 fibrosarcoma cancer cell line

3. Simvastatin Treatment is not Associated with Changes in Serum Concentrations of Heat Shock Proteins -60 and -70 in Patients with Dyslipidemia

4. Inhibitory Effects of Urginea maritima (L.) Baker, Zhumeria majdae Rech. F. and Wendelbo and Physalis divaricata D. Don Ethanolic Extracts on Mushroom Tyrosinase

5. Contact Toxicity and Chemical Composition of Essential Oil of Acantholimon scorpius

6. Comparison of Three Different Diet-Induced Non Alcoholic Fatty Liver Disease Protocols in Rats: A Pilot Study

7. Antibacterial and Antioxidant Activities of the Volatile Composition of the Flower and Fruit of Solanum sisymbriifolium (Litchi Tomato)

8. Radiographic and Histopathologic Analysis on Osteoarthritis Rat Model Treated with Essential Oils of Rosmarinus officinalis and Populus alba

9. Cardioprotective Effects of Rosmarinic Acid on Isoproterenol-Induced Myocardial Infarction in Rats

10. Microextraction of Furosemide from Human Serum and Its Fluorimetric Determination

11. Probing Angiotensin Converting Enzyme (ACE) Domain-Dependent Inhibition of Onopordia, Isolated from Onopordon acanthium L., Using a Continuous Fluorescent Assay

12. Solubility and Apparent Specific Volume of Sucrose in Some Aqueous Polyethylene Glycol Mixtures at 298.2 K

13. Formulation, Characteristic Evaluation, Stress Test and Effectiveness Study of Matrix Metalloproteinase-1 (MMP-1) Expression of Glutathione Loaded Alginate Microspheres and Gel

14. The Ameliorative Effects of Allopurinol on Paraquat-Induced Pulmonary Fibrosis in Rats

15. Apparent Specific Volumes of Sucrose in Different Aqueous Cosolvent Mixtures at 298.2 K

16. Combined Use of Polymers and Porous Materials to Enhance Cinnarizine Dissolution

17. MCF-7 and its Multidrug Resistant Variant MCF-7/ADR Overcome TNF Cytotoxicity through Prevention of Reactive Oxygen Species Accumulation

18. Phytochemicals and Tyrosinase Inhibitory Activity from Piper caninum and Piper magnibaccum

19. Euphorbia prostata Exerts Potent Anti-Inflammatory and Anti-Arthritic Activity in Downregulating the Increased Expression of Pro-Inflammatory Cytokines

20. A Fast and Robust Approach for the Green Synthesis of Spherical Magnetite (Fe3O4) Nanoparticles by Tilia tomentosa (Ihlamur) Leaves and its Antibacterial Studies

21. Antityrosinase Inhibitory Activity of Phytochemicals from Alpinia aquatica Roscoe

22. The Effects of N-acetylcysteine on Inflammatory Markers and Homocysteine: A Systematic Review and Meta-analysis of Randomized Controlled Trials

23. A Comparison on Effects of High Dose Rosuvastatin versus High Dose Atorvastatin on Lipid Profile and CRP Level in Patients Undergoing Percutaneous Coronary Intervention: A Randomized Study

24. Fast-Dissolving Sublingual Nanofibers of Ondansetron Hydrochloride: Formulation, Physicochemical Characterization, and Clinical Evaluation on Post-cataract Surgery Patients

25. Nicolau Syndrome: A Review of Case Studies

26. Design and Evaluation of Novel Sustained-Release Floating Microspheres for Oral Delivery of Ciprofloxacin Hydrochloride

27. Synthesis of Novel Androstane-N-Cyclohexyl-17-Carboxamides, and Their Effect on the 5α-Reductase Isoform 2, the Androgen Receptor, and Androgen-Dependent Glands

28. A Mini Review of Neuropharmacological Effects of Rosa damascena Herrm

29. Development of a Nanocluster-Based Platform for Determination of Sofosbuvir

30. MicroRNA 138 Upregulation is Associated with Decreasing Levels of CCND1 Gene Expression and Promoting Cell Death in Human Prostate Cancer Cell Lines

31. Targeting Pharmacological and Nanotechnology Based Therapeutics for Management of Hirsutism: A Comprehensive State-of-the-Art

32. Response Surface Methodology Approach to Optimize the Expression of Thioredoxin-MOG Fusion Protein

33. Biogenic Zinc Oxide Nanoparticles Attenuate Acute Lymphoblastic Leukemia Cell Proliferation through Oxidative Stress and DNA Damage

34. Can L-Carnitine Replace Tumor Necrosis Factor-Alpha Blockers? A Systematic Review and Dose–Response Meta-Analysis

35. Vesicular Carriers for Follicular Drug Delivery

20. A Fast and Robust Approach for the Green Synthesis of Spherical Magnetite (Fe₃O₄) Nanoparticles by Tilia tomentosa (Ihlamur) Leaves and its Antibacterial Studies

28. **A Mini Review of Neuropharmacological Effects of Rosa damascena Herrm**

30. **MicroRNA 138 Upregulation is Associated with Decreasing Levels of CCND1 Gene Expression and Promoting Cell Death in Human Prostate Cancer Cell Lines**