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April 2025, Vol 31, No. 2

Pharmaceutical Sciences is a peer-reviewed, and quarterly journal providing a forum for basic to clinical issues related to all areas of pharmaceutical sciences. It is the official journal of Faculty of Pharmacy, published by TUOMS PRESS, Tabriz University of Medical Sciences.
- Platinum Open Access (no processing or publication fees)
- Indexed in Web of Science Core Collection (Impact Factor 2023= 1.4) and Scopus (CiteScore 2023= 2.6-Q2)
- Average time to first decision in 2024 (all decisions): 15 days
- Time to first post-review decision in 2024: 2-10 weeks
- Acceptance rate in 2024: 10%
- Publications from 21 countries in 2024

Original Research

1. Mitochondrial Dysfunction as a Mechanism for Pioglitazone-Induced Injury toward HepG2 Cell Line

Hossein Niknahad, Reza Heidari, Abdolsalam Mohammad Alzuhairi, Asma Najibi*

Pharm Sci. 2015;20(4): 169-174.

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Original Research

2. A Comparative Study of Progesterone and Lidocaine Hydrochloride Release from Poly(L-lactide) Films

Arezou Mashak*, Hamid Mobedi, Hamid Mahdavi

Pharm Sci. 2015;21(2): 77-85. doi: 10.15171/PS.2015.21

Scopus ID: 84945354467

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Original Research

3. Propylthiouracil-Induced Liver Injury in Mice and the Protective Role of Taurine

Raziyeh Karamikhah, Akram Jamshidzadeh, Negar Azarpira, Arastoo Saeidi, Reza Heidari*

Pharm Sci. 2015;21(2): 94-101. doi: 10.15171/PS.2015.23

Scopus ID: 84945365028

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Research Article

4. Sulfasalazine-Induced Hepatic Injury in an Ex Vivo Model of Isolated Perfused Rat Liver and the Protective Role of Taurine

Reza Heidari, Nazanin Sadeghi, Negar Azarpira, Hossein Niknahad*

Pharm Sci. 2015;21(4): 211-219. doi: 10.15171/PS.2015.39

Scopus ID: 84954507562

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Research Article

5. Comparison of Three Different Diet-Induced Non Alcoholic Fatty Liver Disease Protocols in Rats: A Pilot Study

Sara Shojaei Zarghani, Hamid Soraya, Leila Zarei, Mohammad Alizadeh*

Pharm Sci. 2016;22(1): 9-15. doi: 10.15171/PS.2016.03

Scopus ID: 84963522493

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Research Article

6. Antimalarial Drugs-Induced Hepatic Injury in Rats and the Protective Role of Carnosine

Akram Jamshidzadeh, Reza Heidari*, Farzaneh Abazari, Maral Ramezani, Forouzan Khodaei, Mohammad Mehdi Ommati, Maryam Ayarzadeh, Roya Firuzi, Arastoo Saeedi, Negar Azarpira, Asma Najibi

Pharm Sci. 2016;22(3): 170-180. doi: 10.15171/PS.2016.27

Scopus ID: 84989960993

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Research Article

7. Preparation and Physicochemical Characterization of Biodegradable mPEG-PCL Core-Shell Micelles for Delivery of Artemisinin

Hamid Reza Kheiri Manjili, Hojjat Malvandi, Mir-Sajjad Mosavi, Hossein Danafar*

Pharm Sci. 2016;22(4): 234-243. doi: 10.15171/PS.2016.37

Scopus ID: 85012927003

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Review

8. Natural Polysaccharide based Nanoparticles for Drug/Gene Delivery

Sara Salatin*, Mitra Jelvehgari

Pharm Sci. 2017;23(2): 84-94. doi: 10.15171/PS.2017.14

Scopus ID: 85023208059

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Research Article

9. The Postulated Hepatotoxic Metabolite of Methimazole Causes Mitochondrial Dysfunction and Energy Metabolism Disturbances in Liver

Hossein Niknahad, Akram Jamshidzadeh, Reza Heidari*, Narges Abdoli, Mohammad Mehdi Ommati, Faezeh Jafari, Mahdi Zarei, Behnam Asadi

Pharm Sci. 2016;22(4): 217-226. doi: 10.15171/PS.2016.35

Scopus ID: 85012926071

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Short Communication

10. An In Vitro Aerosolization Efficiency Comparison of Generic and Branded Salbutamol Metered Dose Inhalers

Sara Rahimkhani, Saeed Ghanbarzadeh, Ali Nokhodchi, Hamed Hamishehkar*

Pharm Sci. 2017;23(1): 77-81. doi: 10.15171/PS.2017.12

Scopus ID: 85018527187

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Research Article

11. A Colon Targeted Delivery System for Resveratrol Enriching in pH Responsive-Model

Hashem Andishmand, Hamed Hamishehkar, Afshin Babazadeh, Arezou Taghvimi, Mohammad Amin Mohammadifar, Mahnaz Tabibiazar*

Pharm Sci. 2017;23(1): 42-49. doi: 10.15171/PS.2017.07

Scopus ID: 85018523068

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Research Article

12. Propylthiouracil-induced mitochondrial dysfunction in liver and its relevance to drug-induced hepatotoxicity

Akram Jamshidzadeh, Hossein Niknahad, Reza Heidari*, Maryam Azadbakht, Forouzan Khodaei, Mohammad Reza Arabnezhad, Omid Farshad

Pharm Sci. 2017;23(2): 95-102. doi: 10.15171/PS.2017.15

Scopus ID: 85023168305

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Research Article

13. Preparation and Characterization of Celecoxib Agglomerated Nanocrystals and Dry Powder Inhalation Formulations to Improve its Aerosolization Performance

Sepideh Mardani, Maryam Maghsoodi, Saeed Ghanbarzadeh, Ali Nokhodchi, Shadi Yaqoubi, Hamed Hamishehkar*

Pharm Sci. 2017;23(4): 278-284. doi: 10.15171/PS.2017.41

Scopus ID: 85040508705

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Research Article

14. Amino Acid-Containing Krebs-Henseleit Buffer Protects Rat Liver in a Long-Term Organ Perfusion Model

Reza Heidari* , Mohammad Mehdi Ommati, Sanya Alahyari, Negar Azarpira*, Hossein Niknahad*

Pharm Sci. 2018;24(3): 168-179. doi: 10.15171/PS.2018.25

Scopus ID: 85055512082

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Research Article

15. Boldine Supplementation Regulates Mitochondrial Function and Oxidative Stress in a Rat Model of Hepatotoxicity

Reza Heidari* , Mohammad Reza Arabnezhad, Mohammad Mehdi Ommati, Negar Azarpira, Elham Ghodsimanesh, Hossein Niknahad*

Pharm Sci. 2019;25(1): 1-10. doi: 10.15171/PS.2019.1

Scopus ID: 85065642747

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Research Article

16. Cytoprotective Properties of Carnosine against Isoniazid-Induced Toxicity in Primary Cultured Rat Hepatocytes

Aziz Eftekhari, Reza Heidari, Elham Ahmadian* , Mohammad Ali Eghbal*

Pharm Sci. 2018;24(4): 257-263. doi: 10.15171/PS.2018.38

Scopus ID: 85059598073

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Review

17. Non-Invasive and Less Degradative Ways of Insulin Administration

Saeideh Allahyari , Yousef Javadzadeh*

Pharm Sci. 2019;25(2): 85-92. doi: 10.15171/PS.2019.14

Scopus ID: 85069179927

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Research Article

18. Protective Effects of Selenium in Patients with Beta-Thalassemia Major

Ajand Aboutalebi, Abolghasem Jouyban , Hadi Chavoshi, Aliakbar Movassaghpour Akbari, Elnaz Shaseb, Parvin Sarbakhsh, Saba Ghaffary*

Pharm Sci. 2020;26(1): 25-31. doi: 10.34172/PS.2019.53

Scopus ID: 85084574074

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Research Article

19. Protective Effects of Ursodeoxycholic Acid on Valproic Acid Induced Hepatotoxicity in Epileptic Children with Recurrent Seizure; A Double-Blinded Randomized Clinical Trial

Iraj Shahramian , Ali Bazi, Rosa Mostafaee, Mohammad Hasan Mohammadi*

Pharm Sci. 2020;26(1): 32-37. doi: 10.34172/PS.2019.62

Scopus ID: 85084553882

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Research Article

20. Improvement of Bioavailability and Dissolution of Tanshinone IIA by Encapsulating it with Hydroxypropyl-β-Cyclodextrin

Jie Yu , Ni Wu, Xiaohui Zheng, Maosheng Zheng*

Pharm Sci. 2020;26(3): 296-305. doi: 10.34172/PS.2020.31

Scopus ID: 85096585381

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Research Article

21. Molecular Dynamics Simulation, Characterization and In Vitro Drug Release of Isoniazid Loaded Poly-ε-caprolactone Magnetite Nanocomposite

Aram dokht khatibi Khatibi* , Zarrin Eshaghi, Hamid Mosaddeghi, Davoud Balarak

Pharm Sci. 2020;26(4): 406-413. doi: 10.34172/PS.2020.36

Scopus ID: 85101547279

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Research Article

22. Design and Evaluation of Novel Sustained-Release Floating Microspheres for Oral Delivery of Ciprofloxacin Hydrochloride

Parisa Soraya Asa , Shahla Mirzaeei*

Pharm Sci. 2022;28(2): 331-339. doi: 10.34172/PS.2021.45

Scopus ID: 85132860922

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Review Article

23. Antioxidant Activity and Nano Delivery of the Most Frequently Applied Stilbene Derivates: A Brief and Recent Review

Syaiful Choiri* , Rafifah Fitriastuti, Firdausi Z. Faradiva, Windy V. Rahayu

Pharm Sci. 2022;28(3): 365-375. doi: 10.34172/PS.2021.71

Scopus ID: 85139862029

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Review Article

24. Active Targeting Gold Nanoparticle for Chemotherapy Drug Delivery: A Review

Azhoma Gumala , Sutriyo Sutriyo*

Pharm Sci. 2022;28(3): 342-354. doi: 10.34172/PS.2021.75

Scopus ID: 85135470727

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Review

25. Lipid Polymeric Hybrid Nanoparticles: Formulation Techniques and Effects on Glioblastoma

Yudhishtir Singh Baghel , Sankha Bhattacharya*

Pharm Sci. 2022;28(2): 174-193. doi: 10.34172/PS.2021.55

Scopus ID: 85132873675

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Research Article

26. **Development of Chitosan–Tripolyphosphate Nanoparticles as Glycopeptide Antibiotic Reservoirs and Ex Vivo Evaluation for Their Potential to Enhance the Corneal Permeation in Ocular Drug Delivery**

Farhad Safari , Shahla Mirzaeei* , Ghobad Mohammadi

Pharm Sci. 2022;28(3): 449-458. doi: 10.34172/PS.2021.62

Scopus ID: 85139837671

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Research Article

27. Comparing Two Equations for Estimation of Kidney Function (Cock-croft-Gault and Glomerular Filtration Rate Assessment in Liver Disease) for Vancomycin Dosing in Adult Liver Transplant Recipients: A Pilot, Randomized Clinical Trial

Yasaman Saee , Simin Dashti-Khavidaki* , Zahra Ahmadinejad , Fereshteh Ghiasvand

Pharm Sci. 2022;28(3): 424-433. doi: 10.34172/PS.2021.79

Scopus ID: 85139834557

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Review Article

28. Recent Trends in Phytosome Nanocarriers for Improved Bioavailability and Uptake of Herbal Drugs

Vijayakumari Mahadevan Hari Priya, Alaganandam Kumaran*

Pharm Sci. 2023;29(3): 298-319. doi: 10.34172/PS.2023.6

Scopus ID: 85164466506

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Review Article

29. Harnessing Nanotechnology for Optimized Herbal Cancer Treatment: A Comprehensive Review of Nanoscale Drug Delivery Systems

Malihe Sadat Razavi, Fatemeh Ahmadi, Pedram Ebrahimnejad* , Abolfazl Akbarzadeh, Masoud Farokhrou, Ali Nokhodchi*

Pharm Sci. 2024;30(2): 153-186. doi: 10.34172/PS.2023.27

Scopus ID: 85189200748

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Research Article

30. The Effect of Oleoylethanolamide Supplementation on Pyroptotic Cell Death in Obese Patients with Non-Alcoholic Fatty Liver Disease: A Double-Blind Randomized Controlled Clinical Trial

Milad Hasankhani , Maryam Saghafi-Asl* , Mohammad Naemi Kermanshahi* , Alireza Ostadrahimi, Helda Tutunchi, Neda Roshanravan, Neda Gilani

Pharm Sci. 2025;31(2): 151-160. doi: 10.34172/PS.024.40860

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Indexing & Abstracting:

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1. Mitochondrial Dysfunction as a Mechanism for Pioglitazone-Induced Injury toward HepG2 Cell Line

2. A Comparative Study of Progesterone and Lidocaine Hydrochloride Release from Poly(L-lactide) Films

3. Propylthiouracil-Induced Liver Injury in Mice and the Protective Role of Taurine

4. Sulfasalazine-Induced Hepatic Injury in an Ex Vivo Model of Isolated Perfused Rat Liver and the Protective Role of Taurine

5. Comparison of Three Different Diet-Induced Non Alcoholic Fatty Liver Disease Protocols in Rats: A Pilot Study

6. Antimalarial Drugs-Induced Hepatic Injury in Rats and the Protective Role of Carnosine

7. Preparation and Physicochemical Characterization of Biodegradable mPEG-PCL Core-Shell Micelles for Delivery of Artemisinin

8. Natural Polysaccharide based Nanoparticles for Drug/Gene Deliv­ery

9. The Postulated Hepatotoxic Metabolite of Methimazole Causes Mitochondrial Dysfunction and Energy Metabolism Disturbances in Liver

10. An In Vitro Aerosolization Efficiency Comparison of Generic and Branded Salbutamol Metered Dose Inhalers

11. A Colon Targeted Delivery System for Resveratrol Enriching in pH Responsive-Model

12. Propylthiouracil-induced mitochondrial dysfunction in liver and its relevance to drug-induced hepatotoxicity

13. Preparation and Characterization of Celecoxib Agglomerated Nanocrystals and Dry Powder Inhalation Formulations to Improve its Aerosolization Performance

14. Amino Acid-Containing Krebs-Henseleit Buffer Protects Rat Liver in a Long-Term Organ Perfusion Model

15. Boldine Supplementation Regulates Mitochondrial Function and Oxidative Stress in a Rat Model of Hepatotoxicity

16. Cytoprotective Properties of Carnosine against Isoniazid-Induced Toxicity in Primary Cultured Rat Hepatocytes

17. Non-Invasive and Less Degradative Ways of Insulin Administration

18. Protective Effects of Selenium in Patients with Beta-Thalassemia Major

19. Protective Effects of Ursodeoxycholic Acid on Valproic Acid Induced Hepatotoxicity in Epileptic Children with Recurrent Seizure; A Double-Blinded Randomized Clinical Trial

20. Improvement of Bioavailability and Dissolution of Tanshinone IIA by Encapsulating it with Hydroxypropyl-β-Cyclodextrin

21. Molecular Dynamics Simulation, Characterization and In Vitro Drug Release of Isoniazid Loaded Poly-ε-caprolactone Magnetite Nanocomposite

22. Design and Evaluation of Novel Sustained-Release Floating Microspheres for Oral Delivery of Ciprofloxacin Hydrochloride

23. Antioxidant Activity and Nano Delivery of the Most Frequently Applied Stilbene Derivates: A Brief and Recent Review

24. Active Targeting Gold Nanoparticle for Chemotherapy Drug Delivery: A Review

25. Lipid Polymeric Hybrid Nanoparticles: Formulation Techniques and Effects on Glioblastoma

26. Development of Chitosan–Tripolyphosphate Nanoparticles as Glycopeptide Antibiotic Reservoirs and Ex Vivo Evaluation for Their Potential to Enhance the Corneal Permeation in Ocular Drug Delivery

27. Comparing Two Equations for Estimation of Kidney Function (Cock-croft-Gault and Glomerular Filtration Rate Assessment in Liver Disease) for Vancomycin Dosing in Adult Liver Transplant Recipients: A Pilot, Randomized Clinical Trial

28. Recent Trends in Phytosome Nanocarriers for Improved Bioavailability and Uptake of Herbal Drugs

29. Harnessing Nanotechnology for Optimized Herbal Cancer Treatment: A Comprehensive Review of Nanoscale Drug Delivery Systems

30. The Effect of Oleoylethanolamide Supplementation on Pyroptotic Cell Death in Obese Patients with Non-Alcoholic Fatty Liver Disease: A Double-Blind Randomized Controlled Clinical Trial

8. Natural Polysaccharide based Nanoparticles for Drug/Gene Delivery

26. **Development of Chitosan–Tripolyphosphate Nanoparticles as Glycopeptide Antibiotic Reservoirs and Ex Vivo Evaluation for Their Potential to Enhance the Corneal Permeation in Ocular Drug Delivery**