Sulfasalazine-Induced Hepatic Injury in an Ex Vivo Model of Isolated Perfused Rat Liver and the Protective Role of Taurine

Reza Heidari ¹, Nazanin Sadeghi ², Negar Azarpira ³, Hossein Niknahad ^1,2 *

Cited by CrossRef: 11

1- Ommati M, Heidari R, Jamshidzadeh A, Zamiri M, Sun Z, Sabouri S, Wang J, Ahmadi F, Javanmard N, Seifi K, Mousapour S, Yeganeh B. Dual effects of sulfasalazine on rat sperm characteristics, spermatogenesis, and steroidogenesis in two experimental models. Toxicology Letters. 2018;284:46 [Crossref]

2- Niknahad H, Heidari R, Mohammadzadeh R, Ommati M, Khodaei F, Azarpira N, Abdoli N, Zarei M, Asadi B, Rasti M, Shirazi Yeganeh B, Taheri V, Saeedi A, Najibi A. Sulfasalazine induces mitochondrial dysfunction and renal injury. Renal Failure. 2017;39(1):745 [Crossref]

3- Akhmadiev N, Galimova A, Akhmetova V, Khairullina V, Galimova R, Agletdinov E, Ibragimov A, Kataev V. Molecular Docking and Preclinical Study of Five-MemberedS,S-Palladaheterocycle as Hepatoprotective Agent. Adv Pharm Bull. 2019;9(4):674 [Crossref]

4- Ommati M, Mobasheri A, Ma Y, Xu D, Tang Z, Manthari R, Abdoli N, Azarpira N, Lu Y, Sadeghian I, Mousavifaraz A, Nadgaran A, Nikoozadeh A, Mazloomi S, Mehrabani P, Rezaei M, Xin H, Mingyu Y, Niknahad H, Heidari R. Taurine mitigates the development of pulmonary inflammation, oxidative stress, and histopathological alterations in a rat model of bile duct ligation. Naunyn-Schmiedeberg's Arch Pharmacol. 2022;395(12):1557 [Crossref]

5- Ommati M, Sabouri S, Retana-Marquez S, Nategh Ahmadi H, Arjmand A, Alidaee S, Mazloomi S, Akhlagh A, Abdoli N, Niknahad H, Jamshidzadeh A, Ma Y, Azarpira N, Asefi Y, Heidari R. Taurine Improves Sperm Mitochondrial Indices, Blunts Oxidative Stress Parameters, and Enhances Steroidogenesis and Kinematics of Sperm in Lead-Exposed Mice. Reprod Sci. 2023;30(6):1891 [Crossref]

6- Heidari R. The footprints of mitochondrial impairment and cellular energy crisis in the pathogenesis of xenobiotics-induced nephrotoxicity, serum electrolytes imbalance, and Fanconi’s syndrome: A comprehensive review. Toxicology. 2019;423:1 [Crossref]

7- Jamshidzadeh A, Niknahad H, Heidari R, Azadbakht M, Khodaei F, Arabnezhad M, Farshad O. Propylthiouracil-induced mitochondrial dysfunction in liver and its relevance to drug-induced hepatotoxicity. Pharm Sci. 2017;23(2):95 [Crossref]

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