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Pharm Sci. 2017;23(2): 95-102. doi: 10.15171/PS.2017.15

Research Article

Propylthiouracil-induced mitochondrial dysfunction in liver and its relevance to drug-induced hepatotoxicity

Akram Jamshidzadeh 1,2, Hossein Niknahad 1,2, Reza Heidari 1 * , Maryam Azadbakht 2, Forouzan Khodaei 2, Mohammad Reza Arabnezhad 2, Omid Farshad 2,3

Cited by CrossRef: 10

1- Heidari R, Mandegani L, Ghanbarinejad V, Siavashpour A, Ommati M, Azarpira N, Najibi A, Niknahad H. Mitochondrial dysfunction as a mechanism involved in the pathogenesis of cirrhosis-associated cholemic nephropathy. Biomedicine & Pharmacotherapy. 2019;109:271 [Crossref]
2- Ommati M, Heidari R, Ghanbarinejad V, Aminian A, Abdoli N, Niknahad H. The neuroprotective properties of carnosine in a mouse model of manganism is mediated via mitochondria regulating and antioxidative mechanisms. Nutritional Neuroscience. 2020;23(9):731 [Crossref]
3- Ghanbarinejad V, Ahmadi A, Niknahad H, Ommati M, Heidari R. Carnosine Mitigates Manganese Mitotoxicity in an In Vitro Model of Isolated Brain Mitochondria. Adv Pharm Bull. 2019;9(2):294 [Crossref]
4- Ommati M, Sabouri S, Retana-Marquez S, Nategh Ahmadi H, Arjmand A, Alidaee S, Mazloomi S, Akhlagh A, Abdoli N, Niknahad H, Jamshidzadeh A, Ma Y, Azarpira N, Asefi Y, Heidari R. Taurine Improves Sperm Mitochondrial Indices, Blunts Oxidative Stress Parameters, and Enhances Steroidogenesis and Kinematics of Sperm in Lead-Exposed Mice. Reprod Sci. 2023;30(6):1891 [Crossref]
5- Abdoli N, Sadeghian I, Mousavi K, Azarpira N, Ommati M, Heidari R. Suppression of cirrhosis-related renal injury by N-acetyl cysteine. Current Research in Pharmacology and Drug Discovery. 2020;1:30 [Crossref]
6- Tsai P, Chang M, Hsin C, Chuang C, Chuang L, Wu W. Antilipotoxicity Activity of Osmanthus fragrans and Chrysanthemum morifolium Flower Extracts in Hepatocytes and Renal Glomerular Mesangial Cells. Mediators of Inflammation. 2017;2017:1 [Crossref]
7- Ommati M, Heidari R, Ghanbarinejad V, Abdoli N, Niknahad H. Taurine Treatment Provides Neuroprotection in a Mouse Model of Manganism. Biol Trace Elem Res. 2019;190(2):384 [Crossref]
8- Farshad O, Ommati M, Yüzügülen J, Jamshidzadeh A, Mousavi K, Ahmadi Z, Azarpira N, Ghaffari H, Najibi A, Shafaghat M, Niknahad H, Heidari R. Carnosine Mitigates Biomarkers of Oxidative Stress, Improves Mitochondrial Function, and Alleviates Histopathological Alterations in the Renal Tissue of Cholestatic Rats . Pharm Sci. 2020;27(1):32 [Crossref]
9- Ommati M, Jamshidzadeh A, Niknahad H, Mohammadi H, Sabouri S, Heidari R, Abdoli N. N-acetylcysteine treatment blunts liver failure-associated impairment of locomotor activity. PharmaNutrition. 2017;5(4):141 [Crossref]

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