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Pharm Sci. 2015;21(4): 184-191. doi: 10.15171/PS.2015.35

Research Article

Effects of Supplementation with Ginger (Zingiber officinale Roscoe) on Serum Glucose, Lipid Profile and Oxidative Stress in Obese Women: A Randomized, Placebo-Controlled Clinical Trial

Vahideh Ebrahimzadeh Attari 1, Sepideh Mahluji 1, Mohammad Asghari Jafarabadi 2, Alireza Ostadrahimi 3 *

Cited by CrossRef: 26

1- Shi J, Hu H, Harnett J, Zheng X, Liang Z, Wang Y, Ung C. An evaluation of randomized controlled trials on nutraceuticals containing traditional Chinese medicines for diabetes management: a systematic review. Chin Med. 2019;14(1) [Crossref]
2- Ashraf H, Heydari M, Shams M, Zarshenas M, Tavakoli A, Sayadi M, Tamagno G. Efficacy of Ginger Supplementation in Relieving Persistent Hypothyroid Symptoms in Patients with Controlled Primary Hypothyroidism: A Pilot Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Evidence-Based Complementary and Alternative Medicine. 2022;2022:1 [Crossref]
3- Rafieipour N, Gharbi N, Rahimi H, Kohansal A, Sadeghi-Dehsahraei H, Fadaei M, Tahmasebi M, Momeni S, Ostovar N, Ahmadi M, Majd S, Mohammadi-Sartang M. Ginger intervention on body weight and body composition in adults: a GRADE-assessed systematic review and dose-response meta-analysis of 27 randomized controlled trials. 2024;82(12):1651 [Crossref]
4- Ebrahimzadeh Attari V, Somi M, Asghari Jafarabadi M, Ostadrahimi A, Moaddab S, Lotfi N. The Gastro-protective Effect of Ginger (Zingiber officinale Roscoe) in Helicobacter pylori Positive Functional Dyspepsia. Adv Pharm Bull. 2019;9(2):321 [Crossref]
5- Mackonochie M, Rodriguez-Mateos A, Mills S, Rolfe V. A Scoping Review of the Clinical Evidence for the Health Benefits of Culinary Doses of Herbs and Spices for the Prevention and Treatment of Metabolic Syndrome. Nutrients. 2023;15(23):4867 [Crossref]
6- Alkhatib D, Jaleel A, Tariq M, Feehan J, Apostolopoulos V, Cheikh Ismail L, Stojanovska L, Dhaheri A. The Role of Bioactive Compounds from Dietary Spices in the Management of Metabolic Syndrome: An Overview. Nutrients. 2021;14(1):175 [Crossref]
7- Shahrajabian M, Sun W, Cheng Q. Clinical aspects and health benefits of ginger (Zingiber officinale) in both traditional Chinese medicine and modern industry. Acta Agriculturae Scandinavica, Section B — Soil & Plant Science. 2019;69(6):546 [Crossref]
8- Van B, Abdalla A, Algarni A, Khalid A, Zengin G, Aumeeruddy M, Mahomoodally M. Zingiber officinale Roscoe (Ginger) and its Bioactive Compounds in Diabetes: A Systematic Review of Clinical Studies and Insight of Mechanism of Action. CMC. 2024;31(7):887 [Crossref]
9- Yagin N, Aliasgari F, Aliasgharzadeh S, Mahdavi R, Akbarzadeh M. The influence of the fatty acid amide hydrolase 385C>A single nucleotide polymorphisms on obesity susceptibility. Mol Biol Rep. 2019;46(5):5049 [Crossref]
10- Morvaridzadeh M, Sadeghi E, Agah S, Fazelian S, Rahimlou M, Kern F, Heshmati S, Omidi A, Persad E, Heshmati J. Effect of ginger ( Zingiber officinale ) supplementation on oxidative stress parameters: A systematic review and meta‐analysis . J Food Biochem. 2021;45(2) [Crossref]
11- Maharlouei N, Tabrizi R, Lankarani K, Rezaianzadeh A, Akbari M, Kolahdooz F, Rahimi M, Keneshlou F, Asemi Z. The effects of ginger intake on weight loss and metabolic profiles among overweight and obese subjects: A systematic review and meta-analysis of randomized controlled trials. Critical Reviews in Food Science and Nutrition. 2019;59(11):1753 [Crossref]
12- Ramírez-Alarcón K, Victoriano M, Mardones L, Villagran M, Al-Harrasi A, Al-Rawahi A, Cruz-Martins N, Sharifi-Rad J, Martorell M. Phytochemicals as Potential Epidrugs in Type 2 Diabetes Mellitus. Front Endocrinol. 2021;12 [Crossref]
13- Carvalho G, Lira-Neto J, Araújo M, Freitas R, Zanetti M, Damasceno M. Effectiveness of ginger in reducing metabolic levels in people with diabetes: a randomized clinical trial. Rev Latino-Am Enfermagem. 2020;28 [Crossref]
14- Asghari-Jafarabadi M, Khalili L. The Effect of Ginger (Zingiber officinale) on Improving Blood Lipids and Body Weight; A Systematic Review and Multivariate Meta-analysis of Clinical Trials. CPD. 2022;28(35):2920 [Crossref]
15- Askari G, Aghajani M, Salehi M, Najafgholizadeh A, Keshavarzpour Z, Fadel A, Venkatakrishnan K, Salehi-sahlabadi A, Hadi A, Pourmasoumi M. The effects of ginger supplementation on biomarkers of inflammation and oxidative stress in adults: A systematic review and meta-analysis of randomized controlled trials. Journal of Herbal Medicine. 2020;22:100364 [Crossref]
16- Pourmasoumi M, Hadi A, Rafie N, Najafgholizadeh A, Mohammadi H, Rouhani M. The effect of ginger supplementation on lipid profile: A systematic review and meta-analysis of clinical trials. Phytomedicine. 2018;43:28 [Crossref]
17- BAYRAKTAR D. ZENCEFİL’İN (ZINGIBER OFFICINALE ROSCOE) İNSAN SAĞLIĞI ÜZERİNE ÇEŞİTLİ TERAPÖTİK ETKİLERİ. 2021;2(2):55 [Crossref]
18- Bin-Meferi M, Shati A, Eid R, El-kott A. Anti-obesity and Anti-hepatosteatosis Effects of Dietary Zingiber officinale Extract in Male Obese Rats. International J of Pharmacology. 2017;13(6):620 [Crossref]
19- Al Dhaheri A, Alkhatib D, Feehan J, Cheikh Ismail L, Apostolopoulos V, Stojanovska L. The Effect of Therapeutic Doses of Culinary Spices in Metabolic Syndrome: A Randomized Controlled Trial. Nutrients. 2024;16(11):1685 [Crossref]
20- Shivananjappa M. Cardioprotective effects of ginger (Zingiber officinale). SAJHP. 2022;4(1):1 [Crossref]
21- Zhu J, Chen H, Song Z, Wang X, Sun Z, Nammi S. Effects of Ginger (Zingiber officinale Roscoe) on Type 2 Diabetes Mellitus and Components of the Metabolic Syndrome: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine. 2018;2018(1) [Crossref]
22- Salih A, Alwan A, Khadim M, Al‐qaim Z, Mardanov B, El‐Sehrwy A, Ahmed Y, Amerizadeh A. Effect of ginger (Zingiber officinale) intake on human serum lipid profile: Systematic review and meta‐analysis. Phytotherapy Research. 2023;37(6):2472 [Crossref]
23- Maqsood M, Naaz S, Bader Ul Ain H, Mushtaq Z, Nasir M, Qamar A. Evaluating the effect of Ginger Powder on Bilirubin, Creatinine, Urea and Uric Acid on Experimental Diabetic Wistar Rats in Randomized Control Trial . PBMJ. 2022;5(1):351 [Crossref]

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