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Pharm Sci. 2015;21(3): 167-174. doi: 10.15171/PS.2015.32

Original Research

Pharmacokinetics and Bioequivalence Study of Amlodipine and Atorvastatin in Healthy Male Volunteers by LC-MS

Hossein Danafar 1,2 * , Mehrdad Hamidi 3

Cited by CrossRef: 16

1- Danafar H, Schumacher U. Simple and sensitive high performance liquid chromatographic (HPLC) method for the determination of the selegiline in human plasma. Cogent Medicine. 2016;3(1):1179244 [Crossref]
2- Andalib S, Molhemazar P, Danafar H. In vitro and in vivo delivery of atorvastatin: A comparative study of anti-inflammatory activity of atorvastatin loaded copolymeric micelles. J Biomater Appl. 2018;32(8):1127 [Crossref]
3- Manjili H, Malvandi H, Mousavi M, Attari E, Danafar H. In vitro and in vivo delivery of artemisinin loaded PCL–PEG–PCL micelles and its pharmacokinetic study. Artificial Cells, Nanomedicine, and Biotechnology. 2018;46(5):926 [Crossref]
4- Kheiri Manjili H, Malvandi H, Mosavi M, Danafar H. Preparation and Physicochemical Characterization of Biodegradable mPEG-PCL Core-Shell Micelles for Delivery of Artemisinin. Pharm Sci. 2016;22(4):234 [Crossref]
5- Danafar H, Jaberizadeh H, Andalib S. In vitro and in vivo delivery of gliclazide loaded mPEG-PCL micelles and its kinetic release and solubility study. Artificial Cells, Nanomedicine, and Biotechnology. 2017;:1 [Crossref]
6- Lee S, Kim H, Kim K, Kang S, Lee S, Yu K, Lee S. Pharmacokinetic comparison of a fixed-dose combination of telmisartan/rosuvastatin/ezetimibe/amlodipine 80/20/10/5 mg and a loose-dose combination of ezetimibe/rosuvastatin 10/20 mg and telmisartan/amlodipine 80/5 mg in healthy male subjects. Naunyn-Schmiedeberg's Arch Pharmacol. 2025; [Crossref]
7- Haghighi A, Shahanipour K, Monajemi R, Yazdanpanahi N, Fouladgar M. Evaluation of the Cytotoxic Effect of Thymol Loaded Albumin-Coated Fe3O4 Magnetic Nanoparticles on MDA-MB-231 Cell Line and the Expression of Autophagic MAP1LC3A Gene. Pharm Chem J. 2023;57(4):486 [Crossref]
8- Nosrati H, Adinehvand R, Manjili H, Rostamizadeh K, Danafar H. Synthesis, characterization, and kinetic release study of methotrexate loaded mPEG–PCL polymersomes for inhibition of MCF-7 breast cancer cell line. Pharmaceutical Development and Technology. 2019;24(1):89 [Crossref]
9- Nosrati H, Salehiabar M, Manjili H, Danafar H, Davaran S. Preparation of magnetic albumin nanoparticles via a simple and one-pot desolvation and co-precipitation method for medical and pharmaceutical applications. International Journal of Biological Macromolecules. 2018;108:909 [Crossref]
10- Zaghloul A, Lila A, Abd-Allah F, Nada A. Probucol Self-Emulsified Drug Delivery System: Stability Testing and Bioavailability Assessment in Human Volunteers . CDD. 2019;16(4):325 [Crossref]
11- Nosrati H, Sefidi N, Sharafi A, Danafar H, Kheiri Manjili H. Bovine Serum Albumin (BSA) coated iron oxide magnetic nanoparticles as biocompatible carriers for curcumin-anticancer drug. Bioorganic Chemistry. 2018;76:501 [Crossref]
12- Silva M, Ribeiro C, Gonçalves V, Tiritan M, Lima Á. Liquid chromatographic methods for the therapeutic drug monitoring of methotrexate as clinical decision support for personalized medicine: A brief review. Biomedical Chromatography. 2018;32(5) [Crossref]
13- Nosrati H, Salehiabar M, Davaran S, Danafar H, Manjili H. Methotrexate-conjugated L-lysine coated iron oxide magnetic nanoparticles for inhibition of MCF-7 breast cancer cells. Drug Development and Industrial Pharmacy. 2018;44(6):886 [Crossref]
14- Wadhwa K, Rana A. A review on liquid chromatographic methods for the bioanalysis of atorvastatin. Futur J Pharm Sci. 2021;7(1) [Crossref]
15- Ramazani A, Keramati M, Malvandi H, Danafar H, Kheiri Manjili H. Preparation and in vivo evaluation of anti-plasmodial properties of artemisinin-loaded PCL–PEG–PCL nanoparticles. Pharmaceutical Development and Technology. 2018;23(9):911 [Crossref]
16- Han Y, Chen L, Liu W, Xin X, Meng L, Chu X, Huang W, Jin M, Gao Z. An HPLC–MS/MS Method for Quantitation of Trelagliptin and Application in a Comparative Pharmacokinetic Study. Bioanalysis. 2019;11(19):1755 [Crossref]
17- Sangeetha D, Vadlamudi M. Stability-indicating method for the determination of assay and quantification of impurities in amlodipine–atorvastatin combination dosage form by RP-HPLC. Journal of Liquid Chromatography & Related Technologies. 2017;40(11):576 [Crossref]

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