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Pharm Sci. 2017;23(3): 172-181. doi: 10.15171/PS.2017.26

Research Article

Prospects of N-Acetylcysteine and Melatonin as Treatments for Tramadol-Induced Renal Toxicity in Albino Rats

Elias Adikwu 1 * , Bonsome Bokolo 2

Cited by CrossRef: 4

1- Sabbaghziarani F, Soleimani P, Eynshikh F, Zafari F, Aali E. Reduced ischemia‐reperfusion oxidative stress injury by melatonin and N‐acetylcysteine in the male rat brain. IBRO Neuroscience Reports. 2024;17:131 [Crossref]
2- Ali H, Afifi M, Saber T, Makki A, Keshta A, Baeshen M, AL-Farga A. Neurotoxic, Hepatotoxic and Nephrotoxic Effects of Tramadol Administration in Rats. J Mol Neurosci. 2020;70(12):1934 [Crossref]
3- Adelakun S, Ogunlade B, Siyanbade J, Chinazo C. Evaluation of the ameliorative potential of Nutritional Dietary supplementation of vitamin B12 following chronic tramadol hydrochloride exposure induced hyperlipidemia, atherogenic indices, and hepato-renal dysfunction by downregulating redox imbalance, NO/iNOS/NF-κB response, caspase-3- activation and DNA fragmentation in rat’s model. Food Chemistry Advances. 2023;2:100286 [Crossref]
4- Fallah M, Moghble N, Javadi I, Bahadoran H, Shahriary A. Effect of Curcumin and N-Acetylcysteine on Brain Histology and Inflammatory Factors (MMP-2, 9 and TNF-α) in Rats Exposed to Arsenic. Pharm Sci. 2018;24(4):264 [Crossref]

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