Logo-ps
Pharm Sci. 2022;28(2): 194-207.
doi: 10.34172/PS.2021.42

Scopus ID: 85132929822
  Abstract View: 359
  PDF Download: 330

Review

Encapsulating Vitamin D: A Feasible and Promising Approach to Combat Its Deficiency

Mina Esmaeili 1,2 ORCID logo, Reza Yekta 3,2 ORCID logo, Abdol-Samad Abedi 4,2, Kiandokht Ghanati 2,5, Robabe Zamani Derav 6, Anahita Houshyarrad 1,2 ORCID logo, Zeinab Saberi Dehkordi 7, Marjan Ajami 8,2* ORCID logo, Maryam Mahmoudzadeh 9,10,11

1 Department of Nutrition Research, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3 Student Research Committee, Department of Food Science and Technology, Faculty of Nutrition and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
4 Department of Research Deputy, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
5 Research and Education Affairs Office of International Affairs, Food Safety Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
6 Hepatology and Nutrition Research Center, Research Institute for Children’s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
7 Department of Chemistry, Isfahan University of Technology, Isfahan, Iran.
8 Department of Food and Nutrition Policy and Planning Research, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
9 Drug Applied Research Center and Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
10 Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
11 Department of Food Science and Technology, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran.
*Corresponding Author: Email: marjan.ajami80@gmail.com

Abstract

Vitamin D (VD) deficiency is a significant issue affecting a large population around the world. As its natural sources are limited, people must constantly fortify their VD. Encapsulating VD increases its bioavailability and stability during processing and storage; hence it has promising potential to avoid VD deficiency. This study reviews current methods of VD fortification and encapsulation. Two predominant methods of VD fortification, i.e., biofortification and direct fortification, are advantageous over VD supplementation. However, significant VD losses occur during processing, storage, and passing across the stomach which can be minimized through encapsulation methods, i.e., micro and nanoencapsulation. Moreover, the capsule features like size, wall-to-core ratio, wall material, carrier oil composition, and encapsulation technique significantly affect VD bioavailability. To assess the optimum encapsulation procedures and possible risks in food fortification, comprehensive in vitro and in vivo studies must be conducted. Depending on the staple food products of a specific region, both VD fortification strategies have great potential in different countries. Besides, the risk of VD overdose due to fortifying a single staple food product is higher than fortifying various staple food products.
First Name
 
Last Name
 
Email Address
 
Comments
 
Security code


Abstract View: 360

Your browser does not support the canvas element.


PDF Download: 330

Your browser does not support the canvas element.

Submitted: 10 Feb 2021
Revision: 27 Jul 2021
Accepted: 29 Jul 2021
ePublished: 04 Aug 2021
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)