Mahboob Nemati
1,2, Sara Nofozi
3, Shirin Ahmadi
4, Farnaz Monajjemzadeh
1,2,5*1 Food and Drug Safety Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
2 Department of Pharmaceutical and Food Control, Tabriz University of Medical Sciences, Tabriz, Iran.
3 Student Research Committee, Tabriz University of Medical sciences, Tabriz, Iran.
4 Central lab, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
5 Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Abstract
Background: Bis-phenol
A (BPA) can migrate into food stuff from packaging materials and accounts for
food contamination. This research was designed to measure BPA contamination in
the Iranian brands of food grade oils and to find out the possible effect of
production date on the amount of BPA migration.
Methods:
Ten well-known and top selling oils packed in various
containers, were selected and sampled according to their batch number and
production date stated on the label. Subsequently, BPA was extracted by reverse
phase dispersive liquid-liquid extraction (RP-DLLME) method and quantified by
HPLC.
Results: The measured quantity of BPA
in the food grade oil was ranged between 0.5 to 4.37 µg/g of oil samples regardless of the date of
production, the Batch Number, and the producing company.
Statistical analysis revealed
that the
difference of BPA content in oil samples did not depend on their production
date.
Conclusion: According to the amount of allowable migration
introduced by European committee, the amount of BPA migration and consequently contamination of almost all
tested samples exceeds SML. Considering the toxic effects reported
especially in fetus and young children,
prompt regulatory interference is needed in this area.