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Pharm Sci. 2016;22(3): 195-202.
doi: 10.15171/PS.2016.31

Scopus ID: 84989832500
  Abstract View: 1986
  PDF Download: 1243

Research Article

Occurrence, Molecular Detection and Antibiotic Resistance Profile of Escherichia coli O157:H7 Isolated from Ready-to-Eat Vegetable Salads in Iran

Hojjat Kouchakkhani 1, Parvin Dehghan 2*, Mir-hassan Moosavy 3, Bahareh Sarmadi 4

1 Student Research Center, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran
2 Nutrition Research Center, Department Food Science and Technology, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran
3 Department of Food Hygiene, Faculty of Veterinary Medicine, Tabriz University, Tabriz, Iran
4 Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, University Putra Malaysia, Selangor, Malaysia
*Corresponding Author: Email: dehghan.nut@gmail.com

Abstract

Background: Escherichia coli O157:H7 is one of the high risk bacteria, found in foods, especially in ready-to-eat products, which causes many disorders such as hemorrhagic colitis, hemolytic uremic syndrome and dysentery in humans. The objective of this study was to determine the contamination of Escherichia coli O157:H7 and antibiotic resistance in ready-to-eat vegetable salads. Methods: In this study, 6o ready-to-eat salad vegetable samples were collected from restaurants for determining their isolated Escherichia coli O157:H7 and their antibiotic resistance by SYBR Green I Based real-time PCR and disc diffusion method, respectively. Results: Out of the 60 samples, 10 samples (16.66%) were positive for Escherichia coli O157:H7.  All identified isolates were resistant to more than five antibiotics. A high rate of resistance was observed to the clindamycin, vancomycin, erythromycin, penicillin, amoxicillin and cephalothin (100%), cefixime (40%), amikacin (20%), cefotaxime and cetracycline (10%). Conclusion: The presence of toxigenic Escherichia coli O157:H7 in ready-to-eat vegetable salads can be considered a public health threat. Providing the useful strategies for improving food safety and inspection services is necessary. Further studies are suggested to identify specific ready-to-eat vegetable salads-related hazards. 
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Submitted: 19 Jan 2016
Accepted: 10 May 2016
ePublished: 30 Sep 2016
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