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Pharm Sci. 2021;27(3): 326-338. doi: 10.34172/PS.2020.101

Research Article

Anti-Inflammatory and Analgesic Activities of 7-Chloro-4-(Piperazin-1-yl) Quinoline Derivative Mediated by Suppression of InflammatoryMediators Expression in Both RAW 264.7 and Mouse Models

Mona Elsayed Aboutabl 1 * ORCID, Ahmed Ragab Hamed 2, Mohamed Farouk Hamissa 3,4, Emad Khairy Ahmed 5

Cited by CrossRef: 7

1- Ragheb A, Masoud M, El Shabrawy M, Farid M, Hegazi N, Mohammed R, Marzouk M, Aboutabl M. MS/MS-based molecular networking for mapping the chemical diversity of the pulp and peel extracts from Citrus japonica Thunb.; in vivo evaluation of their anti-inflammatory and anti-ulcer potential. Scientific African. 2023;20:e01672 [Crossref]
2- Patel N, Maisuria P, Gujarati A, Patel D. Synthesis of Piperazine-containing Derivatives and their Antimicrobial, Antimycobacterial, Antimalarial and Antioxidant Activities. CBC. 2024;20(6) [Crossref]
3- Pavan P, Angajala G, Subashini R, Aruna V. Ultrasound assisted MK-10 catalyzed new benzimidazole bejeweled quinoline molecular hybrids: Facile synthesis, SAR, molecular modelling and biological evaluation as free radical scavengers and antiinflammatory agents. Journal of Molecular Structure. 2024;1305:137702 [Crossref]
4- Aboutabl M, Fayed B, Ismail S. Investigation of chitosan, its depolymerized products, and nanoformulation as novel anticonvulsants. 2022;21(3):385 [Crossref]
5- Aboutabl M, Elkhateeb W, Masoud M, Daba G, Afifi A, Hussein R. HPLC and GC–MS–based metabolic profiles and in vivo anticonvulsant, sedative, and antinociceptive potentials of truffles Tirmania nivea and Tirmania pinoyi hydromethanolic extracts in mice. Biomedical Chromatography. 2022;36(12) [Crossref]
6- Abo-Elmagd M, Hassan R, Aboutabl M, Amin K, El-Azzouny A, Aboul-Enein M. Design, synthesis and anti-inflammatory assessment of certain substituted 1,2,4-triazoles bearing tetrahydroisoquinoline scaffold as COX 1/2-inhibitors. Bioorganic Chemistry. 2024;150:107577 [Crossref]
7- Hamed M, Aboul Naser A, El-Feky A, Elbatanony M, Shaker S, Fayed D, Hassan E, Ali S, Khalil W, Aboutabl M. Phytoconstituents of Red Grape Seeds Extract as Inflammatory Modulator in Adjuvant Arthritic Rats: Role Of IL-1 and its Receptor Blocking. Journal of Biologically Active Products from Nature. 2022;12(3):254 [Crossref]

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