A Comparative Study to Evaluate the Effect of Different Carbohydrates on the Stability of Immunoglobulin G during Lyophilization and Following Storage

Homa Faghihi ¹, Sara Merrikhihaghi ¹, Abdolhosein Ruholamini Najafabadi ¹, Vahid Ramezani ², Soroush Sardari ³, Alireza Vatanara ¹ *

Cited by CrossRef: 9

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2- Wu H, Garidel P, Michaela B. HP-β-CD for the formulation of IgG and Ig-based biotherapeutics. International Journal of Pharmaceutics. 2021;601:120531 [Crossref]

3- Haeuser C, Goldbach P, Huwyler J, Friess W, Allmendinger A. Excipients for Room Temperature Stable Freeze-Dried Monoclonal Antibody Formulations. Journal of Pharmaceutical Sciences. 2020;109(1):807 [Crossref]

4- DİRAMA T. Proteinlerin Camsı Solventlerle Biyolojik Korunması Üzerine Fiziksel Bilgiler: Gliserol, Düşük Sıcaklıklarda Neden Trehaloz'dan Daha İyidir?. 2020;:580 [Crossref]

5- Haeuser C, Goldbach P, Huwyler J, Friess W, Allmendinger A. Be Aggressive! Amorphous Excipients Enabling Single-Step Freeze-Drying of Monoclonal Antibody Formulations. Pharmaceutics. 2019;11(11):616 [Crossref]

6- O’Sullivan A, Ryan K, Padrela L. Production of biopharmaceutical dried-powders using supercritical CO2 technology. The Journal of Supercritical Fluids. 2022;187:105645 [Crossref]

7- Minero A, Runova O, Ustinnikova O, Movsesyants A. Prospects for ion chromatography in quality assessment of biologicals. Biological Products Prevention, Diagnosis, Treatment. 2022;22(2):154 [Crossref]

8- Thakral S, Sonje J, Munjal B, Suryanarayanan R. Stabilizers and their interaction with formulation components in frozen and freeze-dried protein formulations. Advanced Drug Delivery Reviews. 2021;173:1 [Crossref]

9- Madani F, Hsein H, Busignies V, Tchoreloff P. An overview on dosage forms and formulation strategies for vaccines and antibodies oral delivery. Pharmaceutical Development and Technology. 2020;25(2):133 [Crossref]

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