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Pharm Sci. 2018;24(4): 250-256. doi: 10.15171/PS.2018.37

Research Article

Benzylidene Barbituric Acid Derivatives Shown Anticonvulsant Activity on Pentylenetetrazole-Induced Seizures in Mice: Involvement of Nitric Oxide Pathway

Shabnam Mahernia 1, Niusha Sharifi 2, Malihe Hassanzadeh 2, Nastaran Rahimi 3,4, Nastaran Pourshadi 1, Arash Amanlou 5, Ahmad Reza Dehpour 3,4, Massoud Amanlou 1,2 * ORCID

Cited by CrossRef: 7


1- Nazari Montazer M, Asadi M, Bahadorikhalili S, Hosseini F, Amanlou A, Biglar M, Amanlou M. Design, synthesis, docking study and urease inhibitory activity evaluation of novel 2-((5-amino-1,3,4-thiadiazol-2-yl)thio)-N-arylacetamide derivatives. Med Chem Res. 2021;30(3):729 [Crossref]
2- El‐Dash Y, Mahmoud A, El‐Mosallamy S, El‐Nassan H. Electrochemical Synthesis of 5‐Benzylidenebarbiturate Derivatives and Their Application as Colorimetric Cyanide Probe. ChemElectroChem. 2023;10(5) [Crossref]
3- Sahrapeyma S, Shirini F, Mamaghani M. Introduction of a DABCO-Based Ionic Liquid for the Promotion of the Synthesis of Two Important (Thio)barbituric Acid Derivatives. Iran J Sci. 2023;47(5-6):1553 [Crossref]
4- Amanlou A, Nassireslami E, Hosseini F, Dehpour A, Rashidian A, Chamanara M. Synthesis, Docking and Antiepileptic Activity of New 2-((1,5-Diphenyl-1H-1,2,4-Triazol-3-yl)Thio)-N-Phenylacetamide Derivatives. Polycyclic Aromatic Compounds. 2022;42(9):6429 [Crossref]
5- Hajali N, Taghva Manesh A, Seif A. Formations of bimolecular barbituric acid complexes through hydrogen bonding interactions: DFT analyses of structural and electronic features. MGC. 2022;21(1):145 [Crossref]
6- Maadadi R, Benmerache A, Menacer R, Ziani B, Kabouche Z, Saher L, Bachari K, Harakat D. Facile green in situ hemisynthesis of new chiral chromeno-pyrimidine derivatives: antibacterial, antioxidant activities and molecular docking study . Natural Product Research. 2023;:1 [Crossref]
7- Shafiq N, Arshad U, Zarren G, Parveen S, Javed I, Ashraf A. A Comprehensive Review: Bio-Potential of Barbituric Acid and its Analogues. COC. 2020;24(2):129 [Crossref]