Abstract View: 31


Solubilization Methods for Paclitaxel and Docetaxel: An Overview

Fariba Pourkarim ORCID logo, Elaheh Rahimpour, Sima Alvani, Abolghasem Jouyban* ORCID logo


Cancer is still a serious disease with high incidence over the past decades. Many anticancer drugs are discovered and used to treat cancer, among them, taxanes such as paclitaxel and docetaxel have high lipophilicity and low aqueous solubility which is further magnified considering the strong need for administering them by intravenous infusion. Currently, the poor water-solubility of taxanes is improved by prodrug formation, conjugation, inclusion complexation, micellar solubilization and liposome-based formulations. Recent achievement for solubilization of taxanes are reviewed and critically discussed regarding their pharmaceutical and chemical applications.
Keywords: Paclitaxel, Docetaxel, Taxanes, Poor water-solubility, Solubilization methods
First Name
Last Name
Email Address
Security code

Abstract View: 31

Your browser does not support the canvas element.

PDF Download: 0

Your browser does not support the canvas element.

Submitted: 30 Mar 2021
Revision: 30 May 2021
Accepted: 30 May 2021
ePublished: 23 Jun 2021
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)