Elaheh Rahimpour
1 
, Nima Nazemieh
1, Tahir Suleymanov
2, William E. Acree, Jr.
3, Abolghasem Jouyban
1,4* 1 Pharmaceutical Analysis Research Center, Pharmaceutical Sciences Institute, Tabriz University of Medical Sciences, Tabriz, Iran
2 Department of Pharmaceutical Chemistry, Azerbaijan Medical University, Baku, Azerbaijan
3 Department of Chemistry, University of North Texas, Denton, TX 76203, USA
4 Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran
Abstract
In this work the most widely used models applied for mathematical representation of the solubility data of pharmaceutical compounds in binary solvents were briefly reviewed. Then the utilizing SPSS software for solubility data modeling with some well-known mathematical models such as the van’t Hoff, the Apelblat, the combined nearly ideal binary solvent/Redlich-Kister, the Jouyban-Acree and the Jouyban-Acree-van’t Hoff, the modified Wilson, and the λh is described as a video file. The video is prepared in two parts. The first part is a general explanation of solubility and the importance of solubility data modeling. The second part describes how to use SPSS software for data modeling with the mentioned models.