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Pharm Sci. 2021;27(Suppl 1): S50-S67.
doi: 10.34172/PS.2021.6
  Abstract View: 253
  PDF Download: 18

COVID-19

Review

The Clinical Characteristics and Treatment Approaches of COVID-19:A Concise Review

Sajjad Eslamkhah 1, Nazila Alizadeh 1, Khalil Hajiasgharzadeh 1, Masoud Eslamkhah 2, Ahad Mokhtarzadeh 1, Behzad Baradaran 1,3,4* ORCID logo

1 Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
2 Islamic Azad University Central Tehran Branch, Tehran, Iran.
3 Pharmaceutical Analysis Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
4 Neurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Abstract

A series of cases of pneumonia occurred in China in late 2019. For this type of coronavirus, the World Health Organization (WHO) formally identified the condition as a coronavirus disease 2019 (COVID-19). They announced that this disease is the recent main concern of health problems in the world. Transfer of this novel coronavirus (nCoV) from human to human exists predominantly among family members, who have close contact with each other. This review article is provided based on the recent findings of COVID-19, which were retrieved by searching PubMed, Google Scholar, Scopus, and Web of Science until December 2020. Here, we highlighted the coronaviruses types, COVID-19 symptoms, epidemiology of the disease, transmission ways, and nCoV related pneumonia pathogenesis and continue with characteristic features and treatment methods. While no approved treatments are available for this type of infection therapy but several drugs may have potential benefits. It seems that identifying the detailed characteristics of the novel coronavirus disease offers the foundation for further research into the production of effective anti-COVID-19 drugs and vaccines.
Keywords: COVID-19, Pathogenesis, Diagnosis, Treatment, Immune Responses
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Abstract View: 253

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PDF Download: 18

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Submitted: 15 Aug 2020
Revision: 26 Jan 2021
Accepted: 26 Jan 2021
ePublished: 03 Feb 2021
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