Ashish Kumar Gupta
1, Ritam Muhury
1, Deepak Ganjewala
1*1 Amity Institute of Biotechnology, Amity University Uttar Pradesh, Sector-125, Noida-201 303 (UP), India
Abstract
Background: Cymbopogon flexuosus popularly known as lemongrass provides a
lemon scented essential oil which is widely used in flavour and fragrance,
perfumery, food and pharmaceuticals. The aim of the present study was to assess
antimicrobial activities of essential oils of three lemongrass cultivars viz., Pragati, Praman and Suvarna.
Methods: Essential oils were isolated from one
month old plants by hydro-distillation in mini Clevenger apparatus for 2 h.
Antimicrobial activities were determined by agar well diffusion method
Results: Lemongrass oils
exhibited strong antimicrobial activity against all the microbes except E coli.
Mean inhibition zone diameter (mm) against bacteria was ranged 27-38 mm. B.
Subtilis was the most sensitive bacterium to all essential oils. Essential oils
also showed strong antifungal effects against both A. niger and C. albicans
with mean inhibition zone diameter (mm) values 20-26 and 27-29 mm,
respectively. Statistical analyses revealed that antimicrobial activity shown
by essential oils were significant (p < 0.05) against all microorganisms
except B. subtilis and C. albicans (p >> 0.05).
Conclusion: The study revealed strong
antimicrobial potential of the essential oil against pathogenic microbial strains which may be of high
clinical importance in future.