Solmaz Asnaashari
1, Simin Keshavarz
2, Abbas Delazar
3, Yaser Sarvari
4, Parina Asgharian
3,5*1 Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
2 Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
3 Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
4 Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
5 Department of Pharmacognosy, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Abstract
Background: Lepidium
vesicarium (Cruciferae), one of the important medicinal
plants with a long history of medicinal use. The current study was designed to
evaluate the free radical scavenging and antimicrobial activities of the L.
vesicarium EO as one of the Iranian plant species.
Methods:
The compositions of the EO from the aerial parts of L.
vesicarium were analyzed by GC-MS and GC-FID. Furthermore, anti-oxidant and
anti-microbial potentials were investigated via DPPH reagent and disk diffusion
procedure, respectively.
Results:
A total of 18 compounds amounting 97.70% of the oil
have been identified, while Benzyl cyanide (43.94%), Isothio cyanic acid
(22.69%) and Benzyl isothio cyanate (20.69%) were the main constituents. The EO
showed no activity against the free radicals and studied microbial strains
(gram positive and gram negative and also fungi species).
Conclusion:
On the whole, the presence of cyanide derivatives in
studied EO revealed the rational use of this plant in medicine. Comparing with
other genesis of Lepidium, anti-oxidant and anti -microbial properties
of L. vesicarium essential oil were not noticeable.