Tabriz University of Medical Sciences Pharmaceutical Sciences 1735-403X 28 3 2022 07 27 A Review of the Biological Roles of MiR-4800; A Novel Tumor Biomarker with Therapeutic Potential 376 382 10.34172/PS.2021.48 EN Monireh Khordadmehr https://orcid.org/0000-0002-4472-3847 Reyhaneh Matin https://orcid.org/0000-0001-7523-8978 Behzad Baradaran https://orcid.org/0000-0002-8642-6795 Amir Baghbanzadeh https://orcid.org/0000-0002-1261-3213 Farinaz Jigari-Asl https://orcid.org/0000-0001-5710-970X Farzad Katiraee https://orcid.org/0000-0002-8634-4378 Journal Article 10.34172/PS.2021.48 2021 07 16 2021 08 19 MicroRNAs (miRNAs) are known as a group of short noncoding ribonucleic acids (ncRNAs). Mainly, they can manage gene expression at the posttranscriptional level in the essential biological and physiological functions. Significantly, more than 50% of the discovered miRNAs genes are placed in cancer‐related genomic regions, which can act as oncomiR or oncosuppressor. In this regard, growing evidence recently demonstrated the deregulation of miR-4800 in human cancers and non-cancerous diseases. However, little information is available on the biological roles of miR-4800 in cancer initiation, development, and progression. Here, we reviewed the targeting sites and biogenesis functions of the miR‐4800 family in physiological and pathological processes like human cancers, particularly with a particular focusing on the validated specific targets.