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Pharm Sci. 2024;30(2): 274-278.
doi: 10.34172/PS.2024.2
  Abstract View: 94
  PDF Download: 61

Video Article

A Description on the Shake-Flask and Laser Monitoring-Based Techniques for Determination of the Drug’s Solubility

Aynaz Zarghampour 1 ORCID logo, Kimiya Jouyban 2, Vahid Jouyban-Gharamaleki 3,4, Abolghasem Jouyban 1,5, Elaheh Rahimpour 1,6* ORCID logo

1 Pharmaceutical Analysis Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
2 Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.
3 Kimia Idea Pardaz Azarbayjan (KIPA) Science Based Company, Tabriz University of Medical Sciences, Tabriz, Iran.
4 Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
5 Faculty of Pharmacy, Near East University, PO BOX: 99138 Nicosia, North Cyprus, Mersin 10, Turkey.
6 Infectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
*Corresponding Author: Email: rahimpour_e@yahoo.com

Abstract

In the current work, the performance of the shake-flask and laser monitoring-based techniques for the determination of the solubility is described as a video file. The video is prepared in three parts. The first part is a general explanation of solubility and its manual and automatic measurement methods. The second part is about how to perform the shake-flask method to measure drug solubility, and the third part is about how the laser monitoring -based automatic device works to measure drug solubility.

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Submitted: 01 Nov 2023
Revision: 26 Dec 2023
Accepted: 06 Jan 2024
ePublished: 14 Feb 2024
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