Aynaz Zarghampour
1 
, Kimiya Jouyban
2, Vahid Jouyban-Gharamaleki
3,4, Abolghasem Jouyban
1,5, Elaheh Rahimpour
1,6* 1 Pharmaceutical Analysis Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
2 Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.
3 Kimia Idea Pardaz Azarbayjan (KIPA) Science Based Company, Tabriz University of Medical Sciences, Tabriz, Iran.
4 Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
5 Faculty of Pharmacy, Near East University, PO BOX: 99138 Nicosia, North Cyprus, Mersin 10, Turkey.
6 Infectious and Tropical Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Abstract
In the current work, the performance of the shake-flask and laser monitoring-based techniques for the determination of the solubility is described as a video file. The video is prepared in three parts. The first part is a general explanation of solubility and its manual and automatic measurement methods. The second part is about how to perform the shake-flask method to measure drug solubility, and the third part is about how the laser monitoring -based automatic device works to measure drug solubility.