Pharm Sci. 2021;27(3): 439-449.
doi: 10.34172/PS.2020.93
  Abstract View: 298
  PDF Download: 44

Research Article

Risk Factors of Supply Chain in Biopharmaceutical Companies in Iran

Hadi Abbasian 1, Reza Yousefi-Zenouz 2, Akbar Abdollahiasl 1, Mahdi Toroski 1, Shekoufeh Nikfar 1, Mohammadreza Siahi-Shadbad 3, Abbas Kebriaeezadeh 1* ORCID logo

1 Department of Pharmacoeconomics and Pharmaceutical Administration, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
2 Department of Information Technology Management, Kharazmi University, Tehran, Iran.
3 Department of Pharmaceutical and Food Control, Tabriz University of Medical Sciences, Tabriz, Iran.
4 Pharmaceutical Management & Economics Research Center, Tehran University of Medical Sciences, Tehran, Iran.


Background: Supply chain risk management can help companies detect potential hazards,mitigate potential risks, and thereby increase supply chain efficiency. The biopharmaceuticalindustry in Iran has a generic-based pharmerging market. Therefore, identifying risksassociated with the supply chain of those drugs can significantly boost the possibility of successof biopharmaceutical companies. This study is conducted to determine the supply chain riskfactors of biopharmaceuticals companies in Iran.

Methods: The current research work is a qualitative-quantitative study. A systematic review andinterview with experts (n=14) were conducted to identify potential supply chain risks in thebiopharmaceutical industries. To determine the significance of identified risks, Fuzzy screeningmethod was employed to collect the opinions of experts (n=16) in the biopharmaceuticalindustries.

Results: By systematic review and interviews with the biopharmaceutical industry experts, 100potential risks in the biopharmaceutical industry supply chain were identified. These risks weredivided into two general categories namely macro and micro risks. Based on experts’ judgment,77 out of 100 identified risks were eliminated and 23 significant risks were determined. Themost important risks are the Ministry of health (as the regulatory body) conflict of interest, USsanctions, lack of domestic suppliers of essential materials, pseudo-productivity, and moneytransfer related to the bank’s sanctions.

Conclusion: Due to the multitude of present risks and the impossibility of controlling all ofthem, it is recommended that managers and producers focus more on controlling the identifiedsignificant risks.

Keywords: Biopharmaceutical, Supply chain, Risk factors, Fuzzy screening, Risk management
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Submitted: 24 Aug 2020
Revision: 08 Nov 2020
Accepted: 08 Nov 2020
ePublished: 15 Nov 2020
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